Seham Ebrahim

This study identifies TMC5 as essential for mechanoresponsive calcium entry during spermiogenesis, linking mechanical cues to sperm development and male infertility.

This study identifies Pcdh20 as a POU2F3 target gene essential for tuft cell microvillus structure, showing its role in maintaining microvillar rigidity and organization.

This study investigates the role of SEPT9 in intestinal epithelial barrier integrity and inflammation, finding that its loss disrupts tight junctions and increases susceptibility to colitis.

The paper identifies a novel cellular organelle complex called hemifusomes through cryo-electron tomography, revealing their role in intraluminal vesicle biogenesis.

This study identifies a paracellular water secretion pathway in the lacrimal gland regulated by non-muscle myosin IIC, which modulates tight junction permeability and can be targeted for dry eye treatment.

The paper identifies TMC4 and TMC5 at microvillar tips and suggests they may function as ion channels and lipid scramblases, similar to mechanotransduction complexes in stereocilia.

The paper identifies fructose-associated DNA methylation changes in AA colon tissue linked to CRC risk, showing greater effects in right-side colon.