Polina V. Lishko

This study identifies branched-chain amino acid fermentation as an alternative electron sink in mammals under hypoxia, with implications for reductive stress and sperm motility.

The paper identifies components of mammalian sperm nuclear vacuoles using cryo-ET and AlphaFold docking, revealing proteasomes, PA200, and ferritin, and their structural roles.

This study identifies how CatSper channels integrate temperature and pH signals through structural and evolutionary analyses in sperm.

This study identifies two functional domains in SEMG1 that inhibit sperm hyperactivation by suppressing CatSper channel activity, providing insights for non-hormonal male contraception.

This study shows human TMEM95 binds eggs, identifies a binding region via crystallography, and develops antibodies that impair sperm-egg fusion without blocking binding.