Author

James R. Ault

University of LeedsORCID 0000-0002-5131-438XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ahmed M. AmaniD· 1 shared Alessandro DattiiD· 1 shared Antonio N. CalabreseiD· 1 shared Arindam DattaiD· 1 shared Daniel N. Stein· 1 shared Elton ZeqirajiD· 1 shared Francesca ChandleriD· 1 shared Francesco Del GaldoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ahmed M. AmanORCID

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1 paper

Recent·Most cited

BiochemistryNature Structural & Molecular BiologyPeer-reviewedMar 17, 2025

Molecular glues that inhibit deubiquitylase activity and inflammatory signalling

Francesca Chandler, Poli Adi Narayana Reddy, Smita Bhutda…·Elton Zeqiraj

The paper identifies first-in-class inhibitors (BLUEs) that selectively inhibit BRISC complex activity by stabilizing an autoinhibited dimer, reducing interferon-stimulated gene expression.

10 citations

experimental assaydrug response / drug discovery

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