Kirsten A. Reimer

This paper introduces ELXRs, CRISPR-CasX-based epigenetic repressors that use sequential proofreading to enhance specificity and potency by reading chromatin state before DNA methylation.

This paper describes methods for isolating and analyzing nascent RNA using long-read sequencing in budding and fission yeasts to study RNA processing and transcription dynamics.

The paper shows co-transcriptional splicing and 3' end cleavage are functionally linked in mammalian erythropoiesis, with splicing delays and intron retention affecting cleavage efficiency.