Author

Ioanna Deni

Columbia University Irving Medical CenterORCID 0000-0002-5266-8243Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:plant (other)· 2

Frequent Co-Authors

David Armand FidockiD· 2 shared Josefine StriepeniD· 2 shared Adele M. LehaneiD· 1 shared Alexandra E. GouldiD· 1 shared Aloysus K. LawongiD· 1 shared Anna Caroline Campos AguiariD· 1 shared Anna Y. Burkhard· 1 shared Arturo Casas Jr· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

David Armand FidockORCID

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2 papers

Recent·Most cited

Identification of α-azacyclic acetamide-based inhibitors of P. falciparum Na+ pump (PfATP4) with fast-killing asexual blood-stage antimalarial activity by phenotypic screening

Arturo Casas Jr, Leah S. Imlay, Vandana Thathy, Kate J. Fairhurst, Adele M. Lehane, Aloysus K. Lawong, Ioanna Deni, Josefine Striepen, Seungheon Lee, Ashwani Kumar, Chao Xing, Hanspeter Niederstrasser, Bruce A. Posner, Benoı̂t Laleu, Susan A. Charman, , Margaret A. Phillips

This study identifies new antimalarial compounds targeting PfATP4 through phenotypic screening, showing fast-killing activity and resistance patterns consistent with PfATP4 inhibition.

ACS Infectious Diseases · Sep 8, 2025Peer-reviewedMicrobiology

A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo

Stanley C. Xie, Chia-Wei Tai, Craig J. Morton, Li‐Ting Ma, Shih‐Chung Huang, Sergio Wittlin, Yawei Du, Yongbo Hu, Con Dogovski, Mina Salimimarand, Robert Griffin, Dylan B. England, Elisa De La Cruz, Ioanna Deni, Tomas Yeo, , Leann M. Tilley

PLoS Pathogens · Dec 9, 2024Peer-reviewedBiochemistry