Michael David Chan

This paper identifies tGLI1 as a mediator of GBM resistance to CDK4/6 inhibitors and shows that ketoconazole sensitizes GBM to CDK4/6 therapy and chemoradiation.

This study shows that late-life short-term dietary restriction improves intestinal stem cell function and alters DNA methylation in aged mice.

This study develops a 2YS logistic regression model using radiogenomics analysis to predict GBM patient survival based on MRI features and gene associations.