Author

Vincen Wu

Imperial College LondonORCID 0000-0002-5292-9941Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Zoltán TakátsiD· 2 shared Alex MontoyaiD· 1 shared Alexis R. BarriD· 1 shared Betheney R. PennycookiD· 1 shared Bhavik PateliD· 1 shared Boris LenhardiD· 1 shared Carmen Ramírez-MoncayoiD· 1 shared Chad Whilding· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Zoltán TakátsORCID

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2 papers

Recent·Most cited

Multimodal imaging reveals a lysosomal drug reservoir that drives heterogeneous distribution of PARP inhibitors

Carmen Ramírez-Moncayo, Restuadi Restuadi, Guanying Zhang, Daniel Marks, Paula Ortega-Prieto, Emily Doherty, Nathalie Lambie, Chad Whilding, Ivan Andrew, Alex Montoya, Bhavik Patel, Katie Tyson, Betheney R. Pennycook, Lauren Pendergast, Vincen Wu, , Louise Fets

The paper uses multimodal imaging to show that lysosomes act as a reservoir for PARP inhibitors, leading to heterogeneous drug distribution and response in ovarian cancer.

Nature Communications · Mar 17, 2026Peer-reviewedCancer Biology

Mass recalibration for desorption electrospray ionization mass spectrometry imaging using endogenous reference ions.

Paolo Inglese, Helen Xuexia Huang, Vincen Wu, Matthew R. Lewis, Zoltán Takáts

The paper introduces a post-acquisition method to correct mass drift in DESI-MSI data, reducing mass errors by up to 60 ppm and improving molecular annotation and spatial distribution quality.

BMC Bioinformatics · Apr 15, 2022Peer-reviewedBioinformatics