Author
MRC London Institute of Medical SciencesORCID 0000-0003-2223-6770Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Karen E. Brown, Shubhadeep Patra, Andrew Dimond…·Amanda G. Fisher
The paper shows that mouse metaphase chromosomes from different cell types have distinct biomechanical properties, with ESC-derived chromosomes showing conserved force-dependent responses but differing from those of NSCs and preB cells.
Carmen Ramírez-Moncayo, Restuadi Restuadi, Guanying Zhang…·Louise Fets
The paper uses multimodal imaging to show that lysosomes act as a reservoir for PARP inhibitors, leading to heterogeneous drug distribution and response in ovarian cancer.
Andrew Dimond, Do Hyeon Gim, Elizabeth Ing‐Simmons…·Amanda G. Fisher
The paper shows PBK/TOPK phosphorylates Ikaros, Aiolos, and CTCF to displace them from mitotic chromosomes, altering chromatin accessibility at specific zinc finger protein sites.
Dounia Djeghloul, Andrew Dimond, Sherry J. Cheriyamkunnel…·Amanda G. Fisher
The paper shows that loss of H3K9 tri-methylation leads to smaller, more compact mitotic chromosomes and altered transcription factor retention.