Wayne Roberts

This study shows nitric oxide reduces PMP-induced platelet activation by inhibiting ADP release, TxA2 production, and integrin αIIbβ3 upregulation through cGMP-dependent signaling.

The paper identifies senescence-associated enhancer RNAs (SAeRs) and shows their functional role in linking chromatin reprogramming to post-transcriptional regulation of senescence.

This study shows that melanoma cancer-associated fibroblast-derived extracellular vesicles alter the tumor microenvironment and pre-metastatic niche, promoting melanoma metastasis.