Guy Salama

Therapeutic potential of Relaxin-2 in Heart Failure with preserved Ejection Fraction (HFpEF)

This study investigates the therapeutic effects of synthetic Relaxin-2 in HFpEF, showing it reverses diastolic dysfunction and reduces arrhythmia vulnerability in ZSF1 rats.

Cardiomyocyte Targeting Peptide to Deliver Amiodarone

This paper demonstrates that a cardiomyocyte-targeting peptide can deliver amiodarone at a lower dose, reducing cardiac conduction velocity and action potential duration with fewer side effects.

Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies

The paper identifies peripheral neural circuits regulating heart rate in mice using optogenetic and viral vector strategies, revealing distinct roles of cholinergic and noradrenergic neurons.