Peter Mark Carlton

This paper investigates how SPO-11 and its cofactors, particularly DSB-1, regulate meiotic DNA double-strand break formation in C. elegans through dimerization and evolutionary adaptation.

This study shows ZHP-2/HEI10 regulates CO formation in C. elegans by disassembling proCO factors and recruiting Polo kinase to trigger coarsening and crossover execution.

The paper investigates how C. elegans meiotic chromosomes sense length to ensure proper segregation, finding that crossover sites act as diffusion boundaries for a short arm-determining factor.

This paper identifies a meiosis-specific function of the phosphatase GSP-2 in promoting germ cell immortality through small RNA-mediated genome silencing in C. elegans.