Chaoyou Xue

This study identifies two distinct RNA-guided transposition pathways used by IS110 transposons, resolving prior inconsistencies in their mechanism.

This study investigates how crRNA seed sequence mismatches affect interference and priming in the type I-E CRISPR-Cas system, finding that specific mismatches cause significant defects in immune function.

This paper develops a synthetic biology toolkit for Bacillus methanolicus to study plasmid-dependent methylotrophy and enhance methanol-based biosynthesis of L-arginine.

This paper introduces a method that integrates enzymatic and thermodynamic constraints into genome-scale metabolic models to improve pathway prediction accuracy.