Author

Chloe A. N. Gerak

The University of MelbourneORCID 0000-0002-5329-9443Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Dáire Gannon· 2 shared Gordon K. SmythiD· 2 shared Laura CorsoiD· 2 shared Mengbo LiiD· 2 shared Oliver OzaydiniD· 2 shared Stephin J. VervoortiD· 2 shared Aleen Al HalawaniiD· 1 shared Aoife McLysaghtiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMolecular Biology

Dáire Gannon

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2 papers

Recent·Most cited

Termination dynamics set RNAPII elongation rate and gate the response to CDK12 inactivation

Oliver Ozaydin, Lin Liu, Dáire Gannon, Mina Haddawi, Chloe A. N. Gerak, Sarahi Rivera, Laura Corso, Maede Salehi, Mengbo Li, Yining Tian, Tan A. Nguyen, Jafar S. Jabbari, Calvin A. Kraupner-Taylor, Zheng Fan, Jennifer R. Devlin, , Stephin J. Vervoort

The paper identifies SCAF4-CPA and KHDRBS1/SAM68 as key regulators of RNAPII termination under CDK12 inactivation, showing termination dynamics influence elongation rate and response to inhibition.

bioRxiv · Jul 21, 2026 · PreprintMolecular Biology

INTS12 Bridges Integrator and NELF to Prevent the Release of Non-processive RNA Polymerase II Complexes

Laura Corso, S. Rivera, Aleen Al Halawani, Chloe A. N. Gerak, Dáire Gannon, Oliver Ozaydin, Mengbo Li, Kedhar Thyagarajan, Lukasz Niezabitowski, Ngee Kiat Chua, Winnie Tan, Susanne I. Wudy, Aoife McLysaght, Gordon K. Smyth, Shabih Shakeel, , Stephin J. Vervoort

This paper identifies INTS12's role in stabilizing the Integrator-NELF complex to prevent the release of defective RNA Polymerase II complexes, showing its importance in transcription regulation and cellular toxicity.

bioRxiv · Jan 17, 2026 · PreprintMolecular Biology