Author

Bradley Quade

The University of Texas Southwestern Medical CenterORCID 0000-0002-5330-1355Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Dominika BorekiD· 2 shared Josep RizoiD· 2 shared Tabitha Emde· 2 shared Yirui GuoiD· 2 shared Zbyszek OtwinowskiiD· 2 shared A. JoachimiakiD· 1 shared Alexei V. SavchenkoiD· 1 shared Alfa HerreraiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Dominika BorekORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 9, 2026

Cryo-EM structure of detergent-bound Vibrio cholerae MakA captures a candidate intermediate between the soluble form and mature assembly of an α-pore-forming toxin

Yirui Guo, Bradley Quade, Karolina P. Stepien…·Zbyszek Otwinowski

The paper reports a cryo-EM structure of detergent-bound Vibrio cholerae MakA, revealing its conformational changes and role in pore assembly.

DOI 10.64898/2026.09.08.748681

bacteria (other)cryo-EM

Molecular BiologyScience AdvancesPeer-reviewedApr 4, 2025

Structural architecture of TolQ-TolR inner membrane protein complex from opportunistic pathogen Acinetobacter baumannii

Elina M. Karimullina, Yirui Guo, Hanif Muhammad Khan…·Alexei V. Savchenko

The paper presents cryo-EM structures of the TolQ-TolR complex from Acinetobacter baumannii, revealing structural changes related to PMF energy transfer and cell envelope organization.

8 citations

bacteria (other)experimental assay

NeurosciencebioRxivPreprintJul 29, 2021

Control of neurotransmitter release and presynaptic plasticity by re-orientation of membrane-bound Munc13-1

Marcial Camacho, Bradley Quade, Thorsten Trimbuch…·Christian Rosenmund

This study investigates how mutations in the C1C2B region of Munc13-1 affect neurotransmitter release and presynaptic plasticity in murine hippocampal cultures.

DOI 10.1101/2021.07.29.454356

mouseexperimental assay