Author

Dianne A. Cruz

Duke UniversityORCID 0000-0002-5332-6587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Bertrand R. HuberiD· 1 shared Dingjue JiiD· 1 shared Douglas E. WilliamsoniD· 1 shared Emily HockeiD· 1 shared Evon M. DeBose-ScarlettiD· 1 shared Hongyu ZhaoiD· 1 shared Jiawei WangiD· 1 shared Joel E. GelernteriD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenomics

Bertrand R. HuberORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Multi-region spatial transcriptomics reveals region specific differences in response to amyloid beta (Aβ) plaque induced changes in Alzheimer's Disease (AD)

Odmaa Bayaraa, Michael Aksu, Evon M. DeBose-Scarlett, Emily Hocke, Vaibhav Kumar Jain, Shih‐Hsiu J. Wang, Dianne A. Cruz, Simon G. Gregory

This study uses multi-region spatial transcriptomics to identify region-specific transcriptional responses to Aβ plaques in AD, revealing differences in neuronal vulnerability and molecular pathways.

Human Genomics · Nov 29, 2025Peer-reviewedGenomics

Transcriptomic Organization of Human Posttraumatic Stress Disorder

Matthew J. Girgenti, Jiawei Wang, Dingjue Ji, Dianne A. Cruz, the Million Veteran Program, Murray B. Stein, Joel E. Gelernter, Keith Young, Bertrand R. Huber, Douglas E. Williamson, Matthew J. Friedman, John H. Krystal, Hongyu Zhao, Ronald S. Duman

This study identifies transcriptomic changes and genetic factors associated with PTSD using postmortem brain tissue and GWAS data, revealing sex differences and divergence from MDD.

Nature Neuroscience · Dec 21, 2020Peer-reviewedGenomics