Author
The University of MelbourneORCID 0000-0002-5351-1627Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Jessica L Home, Lee Ming Yeoh, Geoffrey Ian McFadden, C.D. Goodman
The paper identifies mutations in apicoplast rRNA genes linked to clindamycin resistance in malaria parasites and shows these mutations reduce mosquito infectivity.
Jordan James Minnell, Mitch Ganley, Ariane R. Lee…·Ian F. Hermans
This study optimizes an mRNA vaccine to enhance liver Trm cell induction by reducing type I interferon responses through improved manufacturing.
Yu Cheng Chua, Lauren E. Holz, Daniel Fernandez‐Ruiz…·William R. Heath
The paper identifies temporal expression patterns of liver-stage malaria antigens and shows that combining antigens with different temporal profiles improves vaccine efficacy.
Shirley Le, Nick Dooley, Declan Murphy…·Lynette Beattie
The paper shows Vγ1+ γδ T cells produce IL-4 to activate DC and CD8 T cells, enhancing immunity against Plasmodium.
Maria N. de Menezes, Zhengyu Ge, Anton J. Cozijnsen…·Daniel Fernandez‐Ruiz
This study shows that RAS vaccination generates long-lived liver-resident memory T cells specific for abundant sporozoite antigens, which mediate protection but may limit vaccine efficacy against diverse parasite strains.
Hayley D. Buchanan, Robyn McConville, Lee Ming Yeoh…·Christopher D. Goodman
The paper shows that azithromycin resistance in malaria parasites reduces their transmission via mosquitoes, suggesting it could help control drug resistance.
Madeline G. Dans, Henni Piirainen, William Nguyen…·Paul R. Gilson
This study identifies MMV020291 as a compound that targets actin-1/profilin dynamics in Plasmodium falciparum, inhibiting red blood cell invasion and apicoplast segregation.