Author

Yu Cheng Chua

The University of MelbourneORCID 0000-0002-7260-5282Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Daniel Fernandez‐RuiziD· 2 shared Justin A. BoddeyiD· 2 shared Lauren E. HolziD· 2 shared Ryan W. J. SteeliD· 2 shared William R. HeathiD· 2 shared A. D. FordiD· 1 shared Anthony Wayne PurcelliD· 1 shared Anton J. CozijnseniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Daniel Fernandez‐RuizORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Chemovaccination with a novel antimalarial targeting the late liver stage induces durable immunity against malaria

Ryan W. J. Steel, Yu Cheng Chua, Waail A. I. Abdalla, Robyn McConville, A. D. Ford, Sabrina Caiazzo, Eva Hesping, Daniel Fernandez‐Ruiz, Lauren E. Holz, William R. Heath, John A. McCauley, David B. Olsen, Justin A. Boddey

This paper demonstrates that chemovaccination using antimalarials targeting plasmepsin IX/X induces durable immunity against malaria in mice and shows conservation of the mechanism in P. falciparum.

Science · Aug 13, 2026Peer-reviewedMicrobiology

Temporal expression of liver-stage malaria antigens shapes vaccine efficacy

Yu Cheng Chua, Lauren E. Holz, Daniel Fernandez‐Ruiz, Sarah L. Draper, R. J. Anderson, Benjamin J. Compton, Ralf B. Schittenhelm, Anton J. Cozijnsen, Charlie Jennison, Sophie L. Collier, Ryan W. J. Steel, Dhilshan Jayasinge, Stéphanie Gras, Justin A. Boddey, Anthony Wayne Purcell, , William R. Heath

The paper identifies temporal expression patterns of liver-stage malaria antigens and shows that combining antigens with different temporal profiles improves vaccine efficacy.

bioRxiv · May 8, 2026 · PreprintImmunology