GeneticsbioRxivPreprint
Reprogramming Factors Activate a Non-Canonical Oxidative Resilience Pathway That Can Rejuvenate RPEs and Restore Vision
Yuancheng Ryan Lu, James C. Cameron, Yan Hu…·Jonathan S. Weissman
OSK factors rejuvenate aged RPE cells by activating a Tet2-independent oxidative resilience pathway through GSTA4, restoring vision and reversing age-related degeneration.
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