Author

Jeroen Pouwels

University of HelsinkiORCID 0000-0002-5388-6103Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Daniel NicoriciiD· 2 shared Johanna MattsoniD· 2 shared Juha T. KlefströmiD· 2 shared Laura NiinikoskiiD· 2 shared Minna MutkaiD· 2 shared Panu E. KovaneniD· 2 shared Rita TurpiniD· 2 shared Ruixian LiuiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Daniel NicoriciORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Microtubule Inhibition Triggers MYC-Mediated Immunogenic Cell Death in Breast Cancer

Ruixian Liu, July Aung, Aino Peura, Antti O. Hiltunen, Linda Id, Mariel Savelius, Martina Peltonen, Rita Turpin, Natasha Salmelin, Johanna M. Anttila, Topi Aulis Tervonen, Ilida Suleymanova, Daniel Nicorici, Minna Mutka, Johanna Mattson, , Juha T. Klefström

The paper identifies microtubule inhibitors as inducers of immunogenic cell death in MYChigh TNBC, linking MYC-dependent DAMP release to immune activation and tumor protection.

bioRxiv · Aug 26, 2025 · PreprintCancer Biology

Patient-derived tumor explant models of tumor immune microenvironment reveal distinct and reproducible immunotherapy responses

Rita Turpin, Karita Peltonen, Jenna H. Rannikko, Ruixian Liu, Anita N. Kumari, Daniel Nicorici, Moon Hee Lee, Minna Mutka, Panu E. Kovanen, Laura Niinikoski, Tuomo J Meretoja, Johanna Mattson, Petrus Järvinen, Kanerva Lahdensuo, Riikka Järvinen, , Juha T. Klefström

The paper evaluates immunomodulatory drug responses in patient-derived tumor explant models of breast and renal cancer, finding reproducible gene expression and cytokine changes across models.

OncoImmunology · Feb 17, 2025Peer-reviewedImmunology