Systems BiologyPLoS PathogensPeer-reviewed
The viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape
Charlotte Vandermeulen, Tina M. O’Grady, Jérôme Wayet…·Jean‐Claude Twizere
This study shows that Tax and HBZ, viral oncoproteins, alter mRNA splicing in T-cells by interacting with spliceosome components, leading to changes in cancer-related genes.