Author

Ambroise Marçais

Hôpital Necker-Enfants MaladesORCID 0000-0002-6844-7920Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:long-read sequencing· 1 Assay:multiome· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

Anne Van den BroekeiD· 2 shared Olivier HermineiD· 2 shared Alice DesbuleuxiD· 1 shared Arsène Burny· 1 shared Bartimée GalvaniD· 1 shared Benoît CharloteauxiD· 1 shared Carole CharlieriD· 1 shared Charlotte VandermeuleniD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersSystems Biology

Anne Van den BroekeORCID

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2 papers

Recent·Most cited

The viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape

Charlotte Vandermeulen, Tina M. O’Grady, Jérôme Wayet, Bartimée Galvan, Sibusiso B. Maseko, Majid Cherkaoui, Alice Desbuleux, Georges Coppin, Julien Olivet, Lamya Ben Ameur, Keisuke Kataoka, Seishi Ogawa, Olivier Hermine, Ambroise Marçais, Marc Thiry, , Jean‐Claude Twizere

This study shows that Tax and HBZ, viral oncoproteins, alter mRNA splicing in T-cells by interacting with spliceosome components, leading to changes in cancer-related genes.

PLoS Pathogens · Sep 20, 2021Peer-reviewedSystems Biology

Pooled CRISPR Inverse PCR sequencing (PCIP-seq): simultaneous sequencing of retroviral insertion points and the integrated provirus with long reads

Maria Artesi, Vincent Hahaut, Fereshteh Ashrafi, Ambroise Marçais, Olivier Hermine, Philip Griebel, Natasa Arsic, Frank J.U.M. van der Meer, Arsène Burny, D Bron, Carole Charlier, Michel Georges, Anne Van den Broeke, Keith Durkin

PCIP-seq uses long-read sequencing to simultaneously identify retroviral insertion sites and their integrated proviruses, revealing SNPs, structural variants, and viral evolution.

bioRxiv · Dec 6, 2019 · PreprintGenomics