Author

Marie Sarazin

Centre National de la Recherche ScientifiqueORCID 0000-0002-5438-8392Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Julien LagardeiD· 3 shared Michel BottlaenderiD· 2 shared Allyson Hinks· 1 shared Anne-Sophie GayiD· 1 shared Audrey Rapinat· 1 shared Axel LegrandiD· 1 shared Benoı̂t DelatouriD· 1 shared Carole Roué-Jagot· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersNeuroscience

Julien LagardeORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintOct 7, 2026

Somatic instability of the C9orf72 repeat expansion in blood differs between patients with amyotrophic lateral sclerosis or frontotemporal dementia.

Mathieu Barbier, Mounir Ichalalen, Maria del Mar Amador…·Isabelle Le Ber

This study uses optical genome mapping to analyze C9orf72 repeat expansion instability in blood from ALS and FTD patients, finding age-dependent differences in repeat size dynamics between conditions.

DOI 10.64898/2026.10.06.26364580

humanDNA methylation

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NeurosciencebioRxivPreprintMay 12, 2026

Experimental and natural peripheral HSV-1 infection: Neurotropism and impact on Alzheimer's disease-related molecular markers

Axel Legrand, Susana Boluda, Marina S. Boukhvalova…·Benoı̂t Delatour

This study investigates the role of HSV-1 infection in Alzheimer's disease by analyzing its impact on Aβ and Tau pathologies in animal models, postmortem brain samples, and AD patients.

DOI 10.64898/2026.05.07.723559

humanspatial transcriptomics

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NeurosciencebioRxivPreprintJan 8, 2025

Large extracellular vesicles containing mitochondria (EVMs) derived from Alzheimer disease cells harbor pathologic functional and molecular profiles and spread mitochondrial dysfunctions

Fanny Eysert, Véronique Legros, Anne-Sophie Gay…·Mounia Chami

This study characterizes large extracellular vesicles containing mitochondria (EVMs) from Alzheimer's Disease cells, showing they carry pathological mitochondrial dysfunction and spread it to recipient cells.

DOI 10.1101/2025.01.08.631851

humanproteomics

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