Susana Boluda

Experimental and natural peripheral HSV-1 infection: Neurotropism and impact on Alzheimer's disease-related molecular markers

This study investigates the role of HSV-1 infection in Alzheimer's disease by analyzing its impact on Aβ and Tau pathologies in animal models, postmortem brain samples, and AD patients.

Somatic instability of the FGF14-SCA27B GAA·TTC repeat reveals a marked expansion bias in the cerebellum

This study examines somatic instability of the FGF14 GAA·TTC repeat in SCA27B, finding a cerebellar-specific expansion bias and increased instability in cerebellar regions compared to other brain areas.

Automated segmentation by deep learning of neuritic plaques and neurofibrillary tangles in brain sections of Alzheimer's Disease Patients

This paper develops a deep learning workflow to automate the segmentation of neuritic plaques and neurofibrillary tangles in Alzheimer's brain sections, achieving high accuracy and consistency across diverse tissue samples.

Pathological changes induced by Alzheimer's brain inoculation in amyloid-beta plaque bearing mice

This study shows that injecting human Alzheimer's brain extracts into mice with amyloid-beta plaques induces tau pathology, memory deficits, and synaptic loss, with neuritic plaques linked to synaptic impairment.