Author

Mounia Chami

Centre National de la Recherche ScientifiqueORCID 0000-0003-1498-7187Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Fanny EysertiD· 3 shared Frédéric ChecleriD· 3 shared Sandra Lacas‐GervaisiD· 3 shared Guillaume DorothéeiD· 2 shared Julien LagardeiD· 2 shared Marie SaraziniD· 2 shared Michel BottlaenderiD· 2 shared Anne-Sophie GayiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersNeuroscience

Fanny EysertORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 8, 2025

Large extracellular vesicles containing mitochondria (EVMs) derived from Alzheimer disease cells harbor pathologic functional and molecular profiles and spread mitochondrial dysfunctions

Fanny Eysert, Véronique Legros, Anne-Sophie Gay…·Mounia Chami

This study characterizes large extracellular vesicles containing mitochondria (EVMs) from Alzheimer's Disease cells, showing they carry pathological mitochondrial dysfunction and spread it to recipient cells.

DOI 10.1101/2025.01.08.631851

humanproteomics

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NeurosciencebioRxivPreprintDec 28, 2024

Hampered AMPK-ULK1 cascade in Alzheimer disease (AD) instigates mitochondria dysfunctions and AD-related alterations that are alleviated by metformin

Arnaud Mary, Samantha Barale, Fanny Eysert…·Mounia Chami

This study shows that impairing the AMPK-ULK1 cascade in Alzheimer's disease leads to mitochondrial dysfunction and AD-related changes, which are improved by metformin treatment.

DOI 10.1101/2024.12.28.630598

humanmouse

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Cell BiologyActa Neuropathologica CommunicationsPeer-reviewedJun 8, 2024

Mitochondria alterations in fibroblasts from sporadic Alzheimer's disease (AD) patients correlate with AD-related clinical hallmarks

Fanny Eysert, Paula Fernanda Kinoshita, Julien Lagarde…·Mounia Chami

The paper examines mitochondrial alterations in fibroblasts from Alzheimer's disease patients and links them to clinical hallmarks and cognitive decline.

15 citations

humanexperimental assay

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