Author
University of PaduaORCID 0000-0002-6310-5147Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Giulia Masi, Gualtiero Alvisi, Patrizia Nespeca, Anna Demarinis, Chiara Frasson, Luisa Barzon, Vanessa Barbaro, Stefano Ferrari, Giorgio Palù, Enzo Di Iorio, Marta Trevisan
This study uses CRISPR/Cas9 to disrupt mutant TP63 alleles in patient-derived cells, improving corneal epithelial proliferation in EEC syndrome.
bioRxiv · Feb 11, 2026 · PreprintGenetics
Sk. Sarif Hassan, Vaishnavi Kodakandla, Elrashdy M Moustafa Mohamed Redwan, Kenneth H. Lundstrom, Pabitra Pal Choudhury, Tarek Mohamed Abd El‐Aziz, Kazuo Takayama, Ramesh J. L. Kandimalla, Amos Lal, Ángel Serrano‐Aroca, Gajendra Kumar Azad, Alaa A. A. Aljabali, Giorgio Palù, Gaurav Chauhan, Parise Adadi, , Vladimir Nikolaevich Uversky
The paper identifies 47 unique truncated ORF8 protein variants in B.1.1.7 SARS-CoV-2 sequences and defines nine possible variants based on physicochemical properties.
PeerJ · Mar 21, 2022Peer-reviewedBioinformatics
Sk. Sarif Hassan, Kenneth H. Lundstrom, Debmalya Barh, Raner José Santana Silva, Bruno Silva Andrade, Vasco Azevedo, Pabitra Pal Choudhury, Giorgio Palù, Bruce D. Uhal, Ramesh J. L. Kandimalla, Murat Seyran, Amos Lal, Samendra P. Sherchan, Gajendra Kumar Azad, Alaa A. A. Aljabali, , Vladimir Nikolaevich Uversky
The paper analyzes S-protein variants of SARS-CoV-2 from six continents, finding North America has the most unique variants, which may spread globally, suggesting travel restrictions and vaccine updates are needed.
International Journal of Biological Macromolecules · Sep 24, 2021Peer-reviewedBioinformatics
Sk. Sarif Hassan, Diksha Attrish, Shinjini Ghosh, Pabitra Pal Choudhury, Vladimir Nikolaevich Uversky, Alaa A. A. Aljabali, Kenneth H. Lundstrom, Bruce D. Uhal, Nima Rezaei, Murat Seyran, Damiano Pizzol, Parise Adadi, Antonio Garcia Soares, Tarek Mohamed Abd El‐Aziz, Ramesh J. L. Kandimalla, , Adam Brufsky
The paper analyzes sequence variations and structural properties of SARS-CoV-2 ORF10 protein to assess its role in viral pathogenicity and potential as a pharmaceutical target.
International Journal of Biological Macromolecules · Apr 16, 2021Peer-reviewedBioinformatics
Sk. Sarif Hassan, Alaa A. A. Aljabali, Pritam Kumar Panda, Shinjini Ghosh, Diksha Attrish, Pabitra Pal Choudhury, Murat Seyran, Damiano Pizzol, Parise Adadi, Tarek Mohamed Abd El‐Aziz, Antonio Garcia Soares, Ramesh J. L. Kandimalla, Kenneth H. Lundstrom, Amos Lal, Gajendra Kumar Azad, , Murtaza M. Tambuwala
This study analyzes the ORF8 protein of SARS-CoV-2 and its mutations across human, bat, and pangolin hosts to understand its role in immune evasion and evolutionary dynamics.
Computers in Biology and Medicine · Apr 15, 2021Peer-reviewedMolecular Biology
Sk. Sarif Hassan, Shinjini Ghosh, Diksha Attrish, Pabitra Pal Choudhury, Vladimir Nikolaevich Uversky, Bruce D. Uhal, Kenneth H. Lundstrom, Nima Rezaei, Alaa A. A. Aljabali, Murat Seyran, Damiano Pizzol, Parise Adadi, Antonio Garcia Soares, Tarek Mohamed Abd El‐Aziz, Ramesh J. L. Kandimalla, , Adam Brufsky
The paper analyzes ACE2 receptors across nineteen species to propose a possible SARS-CoV-2 transmission flow based on receptor-binding domain interactions.
Molecules · Dec 13, 2020Peer-reviewedBioinformatics
Sk. Sarif Hassan, Pabitra Pal Choudhury, Vladimir Nikolaevich Uversky, Guy W. Dayhoff, Alaa A. A. Aljabali, Bruce D. Uhal, Kenneth H. Lundstrom, Nima Rezaei, Murat Seyran, Damiano Pizzol, Parise Adadi, Amos Lal, António Soares, Tarek Mohamed Abd El‐Aziz, Ramesh J. L. Kandimalla, , Adam Brufsky
The paper analyzes variations in SARS-CoV-2 accessory proteins across global proteomes and finds ORF3a has the highest unique variations, suggesting these variations may influence pathogenicity.
bioRxiv · Nov 6, 2020 · PreprintBioinformatics
Enrico Lavezzo, Michele Berselli, Ilaria Frasson, Rosalba Perrone, Giorgio Palù, Alessandra Rosalba Brazzale, Sara N. Richter, Stefano Toppo
The paper identifies and classifies G-quadruplex forming sequences in the genomes of all known human viruses, showing they can be used to classify viruses into families.
PLoS Computational Biology · Dec 13, 2018Peer-reviewedBioinformatics