Author

Nizar Y. Saad

Nationwide Children's HospitalORCID 0000-0002-5453-1152Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Afrooz RashnonejadiD· 2 shared Scott Q. HarperiD· 2 shared Allison M. BradburyiD· 1 shared Ben Kelly· 1 shared Bilal Bayazit· 1 shared Burçak ÖzeşiD· 1 shared Chiranth K. NagarajiD· 1 shared Colin T. MaguireiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Afrooz RashnonejadORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintMay 29, 2026

Single Particle Adsorption and Response Quantification for Functional AAVx Titer and Dose Analysis

Chiranth K. Nagaraj, Truc Kim Nugyen, Kwang Joo Kwak…·Eduardo Reátegui

This paper introduces SPARQ, a method to quantify functional AAV vectors at single-particle resolution, revealing functional heterogeneity and improving dose analysis in gene therapy.

DOI 10.64898/2026.05.28.728583

imagingmicroscopy & imaging analysis

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GeneticsbioRxivPreprintMay 29, 2025

REMEDY: REpair of heterozygous Mutations independent of Exogenous Donor template with high efficiency using allele specific CRISPR targeting and HDR enhancers

Yasemin Sezgin, Genesis Snyder, Noushin Saljoughian…·Meisam Naeimi Kararoudi

REMEDY enables efficient repair of heterozygous mutations in human and mouse cells without exogenous donor DNA by using CRISPR-induced DSBs and HDR enhancers.

DOI 10.1101/2025.05.29.641201

humanmouse

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NeurosciencebioRxivPreprintJul 22, 2022

Posttranslational modifications of the DUX4 protein impact toxic function

Renatta N. Knox, Jocelyn O. Eidahl, Lindsay M. Wallace…·Scott Q. Harper

This study identifies posttranslational modifications of DUX4 that regulate its toxic function in FSHD and suggests potential therapeutic targets.

DOI 10.1101/2022.07.22.501148

humanexperimental assay

𝕏 PostBluesky