Günter Härtel

This study identifies Apolipoprotein E as a key driver of neuroinflammation resolution and recovery from viral encephalitis using a mouse model and patient data.

The paper compares gene expression and inflammatory pathways between SARS-CoV-2 infected K18-hACE2 mice and humans, finding poor gene overlap but strong pathway concordance.

The paper compares DNA methylation analysis using the Mouse Methylation BeadChip and reduced representation bisulphite sequencing in murine colorectal carcinogenesis models, showing similar differential methylation detection with different coverage efficiencies.

The paper identifies five distinct subtypes of colorectal cancer using DNA methylation profiling and links them to specific mutations and gene body methylation patterns.