Molecular BiologybioRxivPreprint
Passaging Human Tauopathy Patient Samples in Cells Generates Heterogeneous Fibrils with a Subpopulation Adopting Disease Folds
Zhikai Zeng, Karen Tsay, Vishnu Vijayan…·Songi Han
The paper shows that cell-passaged tau fibrils from CBD and PSP patients generate heterogeneous fibrils with a subpopulation resembling the original disease fold.
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