Author

Vishnu Vijayan

University of California, Santa Barbara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:simulation· 1

Frequent Co-Authors

Michael P. VigersiD· 2 shared Songi HaniD· 2 shared Alexa Albert· 1 shared Amanda L. WoermaniD· 1 shared Andrew P. LonghiniiD· 1 shared Arina A. NikitinaiD· 1 shared Athena Quddus· 1 shared Austin DuBoseiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Michael P. VigersORCID

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2 papers

Recent·Most cited

Precision Proteoform Design for 4R Tau Isoform Selective Templated Aggregation

Andrew P. Longhini, Austin DuBose, Samuel Lobo, Vishnu Vijayan, Yeran Bai, Erica Keane Rivera, Julia Sala‐Jarque, Arina A. Nikitina, Daniel Carneiro Carrettiero, Matthew Unger, Olivia Sclafani, Valerie Fu, Emily R. Beckett, Michael P. Vigers, Luc Buée, , Kenneth S. Kosik

The paper designs a 19-residue peptide that selectively induces aggregation of 4R tau over 3R tau, revealing structural and amino acid determinants of tauopathy propagation.

Proceedings of the National Academy of Sciences · Apr 3, 2024Peer-reviewedMolecular Biology

Passaging Human Tauopathy Patient Samples in Cells Generates Heterogeneous Fibrils with a Subpopulation Adopting Disease Folds

Zhikai Zeng, Karen Tsay, Vishnu Vijayan, Matthew P. Frost, Shikhar Prakash, Athena Quddus, Alexa Albert, Michael P. Vigers, Madhur Srivastava, Amanda L. Woerman, Songi Han

The paper shows that cell-passaged tau fibrils from CBD and PSP patients generate heterogeneous fibrils with a subpopulation resembling the original disease fold.

bioRxiv · Jul 19, 2023 · PreprintMolecular Biology