Pharmacology & ToxicologybioRxivPreprint
Disruption of the PGE2 synthesis / response pathway restrains atherogenesis in programmed cell death-1 (Pd-1) deficient hyperlipidemic mice
Emanuela Ricciotti, Soon Yew Tang, Antonijo Mrčela…·Garret A. FitzGerald
This study shows that disrupting the PGE2 synthesis or response pathway reduces atherogenesis in PD-1 deficient hyperlipidemic mice through different immune mechanisms.
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