Suhua Feng

This study identifies RRsS1 as a dual-binding scaffold that stabilizes Pol IV transcription complexes to enhance siRNA biogenesis in plant reproduction.

The paper identifies SNPC-1.2 as a female-specific piRNA transcription factor in C. elegans, revealing how gene duplication and functional specialization generate sex-specific piRNA expression.

This study identifies MORC and MOM1 as spatial regulators of RNA Polymerase V chromatin positioning, which influences DNA methylation landscapes in plants.

The paper identifies J-domain proteins as mediators of PKL recruitment to gene promoters, enabling H3.3 deposition and influencing gene expression through interactions with transcription factors and ATRX.

SunTag-NOVA, a SunTag-MQ1v editor adding TRBIP1 and an oligomerizing CHLAMY domain, methylates and silences FWA, FT and TMM in Arabidopsis without the genome-wide off-target methylation seen with TRBIP1 alone.

This study identifies DAF-16/FOXO's role in repressing let-7 microRNA and NHR-23 to maintain multipotency during dauer in C. elegans.

The paper tests two CRISPR-based epigenome editing tools in cassava to induce DNA methylation at susceptibility gene promoters, reducing pathogen infection and showing inheritance patterns.

This paper develops a virus-based system for transgene- and tissue culture-free heritable genome editing in tomato, achieving somatic editing and mutant progeny without transgenic materials.

The paper shows that multiple redundant mechanisms account for most gene silencing downstream of DNA methylation, with loss of these pathways causing widespread derepression and genomic changes.

The paper uses CRISPR interference to methylate promoters of eIF4E genes in cassava, reducing gene expression and disease susceptibility.

The paper shows CDCA7A and CDCA7B maintain CG methylation in centromeric heterochromatin by remodeling H1-containing nucleosomes, with H1 having an inhibitory role.

The paper identifies Arabidopsis REM transcription factors and GDE1 as key regulators of DNA methylation by recruiting RNA Polymerase IV to generate 24nt-siRNAs that direct methylation to specific genomic loci.

The paper shows MORC-1 overexpression in csr-1 mutants drives gene downregulation by altering chromatin states, revealing its role in CSR-1-mediated gene licensing.

The paper shows that Drosophila males produce Su(Ste) piRNAs through 5'-to-3' phased biogenesis triggered by maternally deposited piRNAs, and this process is bypassed when mothers are XXY.

The paper identifies an OGT-TET3 complex that regulates 5mC and 5hmC levels and XCI in female mouse embryonic stem cells.

This study shows that H2A.W and H1 co-regulate heterochromatin accessibility and DNA methylation in flowering plants by modulating H1 deposition and non-CG methylation.

The paper identifies SNPC-1.3 as a male-specific transcription factor that regulates piRNA expression in C. elegans and shows its sex-specific regulation by TRA-1.

The paper shows that Klp10A mediates Piwi shuttling between nucleus and nuage during mitosis, linking nuclear and cytoplasmic piRNA silencing arms.

The paper identifies MBD9 as an interacting protein of the Arabidopsis SWR1-C complex required for H2A.Z deposition at specific gene loci.