BiochemistrybioRxivPreprint
Phase separation as a concentrating mechanism of protein/peptide hormones for the secretory granule storage
Semanti Mukherjee, Debkanya Sengupta, Prasad Sulkshane…·Samir Kumar Maji
This study shows that protein/peptide hormones undergo phase separation at the TGN, forming amyloid-like structures that enable efficient storage and regulated release in secretory granules.
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