Velociraptor identifies and searches for novel cell types across platforms using hallmark feature sets, revealing new biological insights in glioblastoma and immunology.

Cytometry Part A · Sep 1, 2026Peer-reviewedSystems Biology

Distinct Type 1 Immune Networks Underlie the Severity of Restrictive Lung Disease after COVID-19

Glenda Canderan, Lyndsey M. Muehling, Alexandra Kadl, Shay Ladd, Catherine A. Bonham, Claire E. Cross, Sierra M. Lima, Xihui Yin, Jeffrey M. Sturek, Jeffrey M. Wilson, Behnam Keshavarz, Kyle B. Enfield, Chintan Ramani, Naomi Bryant, Deborah D. Murphy, , Judith A. Woodfolk

The paper identifies distinct type 1 immune networks associated with varying severities of restrictive lung disease following COVID-19.

Nature Immunology · Mar 26, 2025Peer-reviewedImmunology

IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma

Stephanie Medina, Asa A. Brockman, Claire E. Cross, Madeline Hayes, Bret C. Mobley, Akshitkumar M. Mistry, Silky Chotai, Kyle D. Weaver, Reid C. Thompson, Lola Blackwell Chambless, Rebecca A. Ihrie, Jonathan Michael Irish

This study identifies IL-8 as a key factor instructing macrophage identity in glioblastoma, showing IL-8 is necessary for generating CD32+ M_IL-8 macrophages in tumors contacting the lateral ventricle.

bioRxiv · Mar 29, 2024 · PreprintCancer Biology