Author

Madeline Hayes

University of Colorado AnschutzORCID 0000-0003-3684-9885Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Jonathan Michael IrishiD· 2 shared Rebecca A. IhrieiD· 2 shared Akshitkumar M. MistryiD· 1 shared Asa A. BrockmaniD· 1 shared Bret C. MobleyiD· 1 shared Claire E. CrossiD· 1 shared Hannah L. ThirmaniD· 1 shared John A. Jr. PorcoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersSystems Biology

Jonathan Michael IrishORCID

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2 papers

Recent·Most cited

Systems BiologyCommunications BiologyPeer-reviewedJul 31, 2025

Single Cell Profiling Distinguishes Leukemia-Selective Chemotypes

Hannah L. Thirman, Madeline Hayes, Laura C. Geben…·Jonathan Michael Irish

The paper screens a compound library to identify leukemia-selective chemotypes using single-cell profiling and finds that certain rocaglate derivatives selectively induce DNA damage in leukemia cells.

3 citations

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintMar 29, 2024

IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma

Stephanie Medina, Asa A. Brockman, Claire E. Cross…·Jonathan Michael Irish

This study identifies IL-8 as a key factor instructing macrophage identity in glioblastoma, showing IL-8 is necessary for generating CD32+ M_IL-8 macrophages in tumors contacting the lateral ventricle.

2 citations

humanproteomics

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