Author

Matthew L. Schwartz

Howard Hughes Medical InstituteORCID 0000-0002-5542-9109Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Research Focus:perturbation response prediction· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Erik M. JørgenseniD· 2 shared Aaron D. WolfeiD· 1 shared Andrea Cuentas-CondoriiD· 1 shared Cornelia I. BargmanniD· 1 shared Daniel A. Colón‐RamosiD· 1 shared Likui FengiD· 1 shared M. Wayne DavisiD· 1 shared Margaret S. EbertiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Erik M. JørgensenORCID

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2 papers

Recent·Most cited

NeuroscienceeLifePeer-reviewedJun 25, 2026

SynaptoTagMe: A Toolkit for In Vivo Mapping and Modulating Neurotransmission at Single-Cell Resolution

Andrea Cuentas-Condori, Patricia Chanabá-López, Matthew Thomas…·Daniel A. Colón‐Ramos

SynaptoTagMe enables in vivo mapping and modulation of neurotransmission at single-cell resolution in C. elegans by fluorescently labeling and ablating vesicular transporters.

DOI 10.7554/elife.108675

C. elegansimaging

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GeneticsPLoS GeneticsPeer-reviewedNov 8, 2021

High-efficiency CRISPR gene editing in C. elegans using Cas9 integrated into the genome

Matthew L. Schwartz, M. Wayne Davis, Matthew S. Rich, Erik M. Jørgensen

The paper presents C. elegans strains with constitutively expressed Cas9 from integrated transgenes, significantly improving CRISPR editing efficiency and reducing workload.

44 citations

C. elegansCRISPR screen

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