Margaret S. Ebert

SynaptoTagMe enables in vivo mapping and modulation of neurotransmission at single-cell resolution in C. elegans by fluorescently labeling and ablating vesicular transporters.

The paper shows that molecularly aged ribosomes alter translational dynamics by impairing elongation and increasing ribosome collisions during organismal aging.

The paper compares mating behaviors between female and hermaphrodite nematodes, finding differences in chemotaxis and receptivity linked to the ODR-7 transcription factor and sperm presence.

This study identifies cell-specific insulin/IGF signaling mechanisms in C. elegans that regulate presynaptic glutamate release during aversive olfactory learning.