Benedict Anchang

This study identifies two distinct roles of GLIS3 in β-cell development, showing its critical function in bipotent progenitor generation and preβ-to-β cell differentiation, contributing to neonatal diabetes in GLIS3-deficient mice.

This study uses CyTOF to profile circulating tumor cells in SCLC patients, identifying subtype-specific markers and treatment response correlations.

The paper identifies a negative feedback loop where MYC suppresses KDM5B, leading to increased cell survival and tumor progression.

The paper maps EMT and MET states in lung cancer using single-cell resolution and a novel computational tool, showing differences in trajectories and providing a framework for clinical sample characterization.

The paper presents a large-scale cancer pharmacogenomic screen with 11,576 experiments on 910 drug combinations across 85 cancer cell lines, enabling crowd-sourced prediction of synergistic drug pairs and biomarkers.