Jeffrey B. Woodruff

The paper identifies ZYG-9/ch-TOG as a spindle pole protein that binds DNA and packages meiotic chromosomes into polar bodies, ensuring proper genome copy number in oocytes.

The paper identifies a bipartite degron in Cep192 that allows TRIM37 to ubiquitinate and regulate centrosome proteins.

This study shows that PLK-1 phosphorylation of SPD-5 modulates the viscoelastic properties of the PCM scaffold in C. elegans embryos, affecting its size, integrity, and function.

The paper demonstrates that CDK5RAP2 can form minimal centrosome-like structures in vitro, recruiting and activating gamma tubulin ring complexes to generate microtubule asters, and identifies key features of centrosome function.

The paper uses cryo-electron tomography to visualize centrosomes in C. elegans embryos, revealing structural features and differences in microtubule organization during the cell cycle.

This study identifies eIF4ET's role in maintaining oocyte proteome stability during long-term storage by forming condensates, with implications for age-related infertility.

This study identifies ZNF692 as a nucleolar scaffold that enhances 40S ribosome maturation and translation efficiency in rapidly proliferating cells, particularly in cancer cells.

The paper shows that phase separation of C. elegans centrosome proteins forms microtubule organizing centers by concentrating tubulin.