Toru Nakazawa

A sequential, RNA-derived, modified adenosine pathway safeguards cellular metabolism

The paper shows that modified adenosines from RNA catabolism are sequentially metabolized to prevent toxicity and maintain metabolic balance.

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma and includes a genetic link with Alzheimer's disease

Systematic detection of Mendelian and non-Mendelian variants associated with retinitis pigmentosa by genome-wide association study

This study uses GWAS to identify Mendelian and non-Mendelian variants associated with retinitis pigmentosa, uncovering new genetic causes and therapeutic targets.

A frequent variant in the Japanese population determines quasi-Mendelian inheritance of rare retinal ciliopathy

The paper identifies a common variant in the Japanese population that shows quasi-Mendelian inheritance patterns in rare retinal ciliopathy.

Combined inhibition of apoptosis and necrosis promotes transient neuroprotection of retinal ganglion cells and partial axon regeneration after optic nerve damage

This study shows that combining inhibition of apoptosis and necrosis can transiently protect retinal ganglion cells and promote partial axon regeneration after optic nerve damage.