Yasunori Saheki

The paper shows that modified adenosines from RNA catabolism are sequentially metabolized to prevent toxicity and maintain metabolic balance.

This study evaluates kalium channelrhodopsins (KCRs) as optogenetic inhibitors in Drosophila, C. elegans, and zebrafish, showing they are effective and have improved properties compared to chloride-conducting ACRs.

This study identifies a gain-of-function mutation in the UNC-2/CaV2α channel in C. elegans that causes hyperactivity and excitation-dominant synaptic transmission by altering cholinergic and GABAergic transmission.