Larry I. Benowitz

This study identifies the intracellular domain of LIFR/CD118 as essential for optic nerve regeneration in mature RGCs, independent of LIF and other therapies.

This paper identifies a signaling pathway in the mouse retina involving Kv2.1, GLT-1, and NOS1 that promotes optic nerve regeneration after injury.

This paper shows that disrupting G3BP1 granules promotes axon regeneration in both CNS and PNS injuries, suggesting a therapeutic strategy for neural repair.

This study shows that preconditioning with lens injury enhances optic nerve regeneration without genetic manipulations, achieving full-length regeneration through immune-related mechanisms.

The paper identifies REST/NRSF as a suppressor of CNS axon regeneration using systems biology approaches and validates its role through genetic manipulations.

This study shows that combining inhibition of apoptosis and necrosis can transiently protect retinal ganglion cells and promote partial axon regeneration after optic nerve damage.