Author

Indrajit Lahiri

University of SheffieldORCID 0000-0002-5633-7978Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:cryo-EM· 3 Research Focus:protein structure prediction· 2 Organism:yeast· 2 Assay:electronic health records· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Frank DiMaioiD· 2 shared Anamika KumariiD· 1 shared Andres E. Leschziner· 1 shared Andrés E. LeschzineriD· 1 shared B.-G. Han· 1 shared Dong WangiD· 1 shared Janice D. PataiD· 1 shared Jun XuiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Frank DiMaioORCID

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4 papers

Recent·Most cited

Structural basis of multitasking by the apicoplast DNA polymerase from Plasmodium falciparum

Anamika Kumari, Theodora Enache, Timothy D. Craggs, Janice D. Pata, Indrajit Lahiri

This study determines the structural basis of multitasking by the apicoplast DNA polymerase from Plasmodium falciparum using cryoEM, revealing how it balances replicative and lesion bypass synthesis.

Nucleic Acids Research · Oct 14, 2025Peer-reviewedBiochemistry

CryoEM Reconstruction of Yeast ADP-Actin Filament at 2.5 Angstrom resolution. A comparison with mammalian and avian F-actin.

Sarah Stevenson, Svetomir B. Tzokov, Indrajit Lahiri, Kathryn R. Ayscough, Per A. Bullough

The paper reports a 2.5 Å cryo-EM structure of budding yeast F-actin and compares it with mammalian and avian F-actin, identifying key structural differences.

Structure · Jan 10, 2025Peer-reviewedBiochemistry

3.1A structure of yeast RNA polymerase II elongation complex stalled at a cyclobutane pyrimidine dimer lesion solved using streptavidin affinity grids

Indrajit Lahiri, Jun Xu, B.-G. Han, Juntaek Oh, Dong Wang, Frank DiMaio, Andrés E. Leschziner

The paper solves a high-resolution structure of a stalled RNA polymerase II elongation complex using streptavidin affinity grids to overcome air-water interface interactions.

Journal of Structural Biology · Jun 11, 2019Peer-reviewedMolecular Biology

An integrated, pipeline-based approach for cryo-EM structure determination and atomic model refinement in the cloud

Michael A. Cianfrocco, Indrajit Lahiri, Frank DiMaio, Andres E. Leschziner

The paper develops cloud-based software tools for cryo-EM structure determination and atomic model refinement, reducing barriers for new users.

bioRxiv · Jan 11, 2018 · PreprintBiochemistry