Camila Valenzuela

This study shows Salmonella can replicate in macrophages without Type III Secretion Systems if provided with preferred nutrients, highlighting the role of host metabolic heterogeneity in bacterial replication.

This study identifies mechanoporation via the Type Three Secretion System as a mechanism by which Shigella flexneri breaches vacuolar membranes to access the cytosol.

The paper develops a flow cytometry-based method combined with ultra-sensitive proteomics to study host-pathogen interactions in Salmonella-infected macrophages, revealing new insights into virulence factor induction and phagosomal dynamics.

This study identifies SifA as a key effector that prevents Salmonella dormancy by promoting nutrient accessibility through SIF-mediated remodeling of the Salmonella-containing vacuole.