Author
Biomedical Research Networking Center on Neurodegenerative DiseasesORCID 0000-0002-5680-5057Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Alba Nicolau, Marta González-Sepúlveda, Joana M. Cladera-Sastre…·Miquel Vila
This study identifies a bidirectional pathogenic relationship between alpha-synuclein and neuromelanin in Parkinson's disease, showing they promote each other's accumulation and neuronal loss.
Lucas Blasco-Agell, Meritxell Pons‐Espinal, Veronica Testa…·Antonella Consiglio
LRRK2 G2019S iPSC-derived microglia exposed to neuromelanin, but not α-synuclein fibrils, reduce healthy dopaminergic neuron numbers in co-culture; ivermectin prevents this, and post-mortem midbrain supports it.
Marta González-Sepúlveda, Joan Compte, Thaïs Cuadros…·Miquel Vila
This study reduces age-related neuromelanin accumulation in a humanized rodent model, mitigating Parkinson's disease features by preserving dopamine homeostasis and neuronal integrity.