Author

Chen Liu

Hôpital Maisonneuve-RosemontORCID 0000-0002-5693-8634Unclaimed ORCID profile · follow to get notified of new preprints

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Chen Liu6 papers · Yale University

Biology Disciplines

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Christopher E. RuddiD· 2 shared Thai Hien TuiD· 2 shared Alexandra KazanovaiD· 1 shared Ami GrunbaumiD· 1 shared Andres OroyaiD· 1 shared Atena Nemati· 1 shared Auryane Laure Cabald· 1 shared Bastien Moës· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Christopher E. RuddORCID

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2 papers

Recent·Most cited

GSK-3 regulates CD4-CD8 cooperation needed to generate super-armed CD8+ cytolytic T cells against tumors

Bastien Moës, Janna Krueger, Alexandra Kazanova, Chen Liu, Yunfeng Gao, Nikhil Ponnoor Anto, Linda Castoun-Puckett, Andres Oroya, Lan Huong, Auryane Laure Cabald, Thai Hien Tu, Christopher E. Rudd

This study shows GSK-3 enhances PD-1 blockade by promoting CD4-CD8 T-cell cooperation, leading to more effective anti-tumor CD8+ cytolytic T cells.

bioRxiv · Mar 8, 2025 · PreprintImmunology

The identification of a SARs-CoV2 S2 protein-derived peptide with super-antigen-like stimulatory properties on T-cells

Thai Hien Tu, Fatima Ezzahra Bennani, Nasser Masroori, Chen Liu, Atena Nemati, Nicholas Rozza, Ami Grunbaum, Richard B. Kremer, Catalin Milhalcioiu, Denis‐Claude Roy, Christopher E. Rudd

The paper identifies a SARS-CoV-2 S2 protein-derived peptide (P3) with super-antigen-like properties that stimulate T-cells and induce proinflammatory cytokines in mice.

Communications Biology · Jan 6, 2025Peer-reviewedImmunology