Author

Bryan A. Nerger

Harvard UniversityORCID 0000-0002-5702-1844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

David J. MooneyiD· 2 shared Chris H. RycroftiD· 1 shared Fatemeh Tavakoli JoorabiiD· 1 shared Joshua M. BrockmaniD· 1 shared Kyle H. ViningiD· 1 shared L. MahadevaniD· 1 shared Nicholas C. JeffreysiD· 1 shared Nicholas J. DerriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

David J. MooneyORCID

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2 papers

Recent·Most cited

Mechanical cues of an interpenetrating polysaccharide matrix regulate self-assembly of collagen fibers

Fatemeh Tavakoli Joorabi, Nicholas J. Derr, Zecheng Li, Bryan A. Nerger, Chris H. Rycroft, David J. Mooney, Kyle H. Vining

This study shows that the viscoelastic properties of an alginate ECM regulate collagen fiber self-assembly through mechanical coupling.

Science Advances · Sep 2, 2026Peer-reviewedBioengineering

Substrate mediated mechanical forces enable optimal kinetic proofreading by T-cell receptors

Nicholas C. Jeffreys, Joshua M. Brockman, Tiam Heydari, Bryan A. Nerger, Wei‐Hung Jung, Peter W. Zandstra, L. Mahadevan, David J. Mooney, Suraj Shankar

This study shows how mechanical forces and substrate properties enhance T-cell receptor proofreading by delaying decision-making and improving ligand discrimination.

bioRxiv · May 14, 2026 · PreprintBiophysics