Author

Marco Boccitto

National Cancer InstituteORCID 0000-0002-5722-9186Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew C. FlemingiD· 1 shared Elizabeth L. DaleyiD· 1 shared Eric Nathaniel AndersoniD· 1 shared Evangelos KiskinisiD· 1 shared Ivan R. SasselliiD· 1 shared Juan Alberto OrtegaiD· 1 shared Justin K. IchidaiD· 1 shared Kohei SatoiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Andrew C. FlemingORCID

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1 paper

Recent·Most cited

CLIP-Seq Analysis Enables the Design of Ribosomal RNA Bait Oligonucleotides That Protect Against C9orf72 ALS/FTD-Associated Poly-GR Pathophysiology

Juan Alberto Ortega, Ivan R. Sasselli, Marco Boccitto, Andrew C. Fleming, Tyler R. Fortuna, Yichen Li, Kohei Sato, Tristan D. Clemons, Elizabeth L. Daley, Thao Phuong Nguyen, Eric Nathaniel Anderson, Justin K. Ichida, Udai Bhan Pandey, Sandra L. Wolin, Samuel Isaac Stupp, Evangelos Kiskinis

The paper identifies that poly-GR binds ribosomal RNA and shows that modified rRNA oligonucleotides can mitigate poly-GR toxicity in models of C9orf72 ALS/FTD.

bioRxiv · Dec 30, 2022 · PreprintNeuroscience