Author

Cyrus Michael Ghajar

Fred Hutch Cancer CenterORCID 0000-0002-5760-7159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Amelia R. WilhelmiD· 1 shared Andrew J. SnyderiD· 1 shared Anna ElziD· 1 shared Annalyssa Long· 1 shared Carolyn ShashaiD· 1 shared Ekram A. Gad· 1 shared Emma BinghamiD· 1 shared Evan William NewelliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Amelia R. WilhelmORCID

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1 paper

Recent·Most cited

ImmunologyScience ImmunologyPeer-reviewedMar 6, 2026

Modulating AP-1 enables CAR-T cells to establish an intratumoral PD-1+Tcf1+ stem-like reservoir and overcomes resistance to PD-1 axis blockade

Andrew J. Snyder, Sarah M. Garrison, Mitchell G. Kluesner…·Shivani Srivastava

This study shows that overexpressing c-Jun in CAR-T cells enhances their ability to maintain PD-1+Tcf1+ stem-like cells in tumors and improves response to PD-L1 blockade.

4 citationstop 1%

mousebulk RNA-seq