Donald F. Hunt

The paper shows CDK8 phosphorylates DELLA to limit Mediator recruitment, affecting GA signaling in Arabidopsis.

This study shows that SPINDLY-mediated O-fucosylation of ARF6 and ARF8 inhibits their interaction with the coactivator Mediator complex, reducing fruit growth in Arabidopsis.

This study identifies TTLL4 as a therapeutic target in NPM1-mutated AML by showing its role in stabilizing NPM1c and promoting differentiation block, with a small molecule inhibitor demonstrating efficacy.

This paper characterizes protamines in the noble false widow spider Steatoda nobilis, revealing liquid-liquid phase separation during spermiogenesis and evolutionary links to histone H1.

The paper investigates the substrate preferences and functional consequences of Type I and II PRMTs by inhibiting them in A549 cells and analyzing proteomic and transcriptomic changes.