Author

Irene Mariam Roy

Albert Einstein College of MedicineORCID 0000-0002-9858-1207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alexandra SchureriD· 1 shared Benjamin M. LortoniD· 1 shared Daniel K. BorgeriD· 1 shared David ShechteriD· 1 shared Donald F. HuntiD· 1 shared Ellen AngelesiD· 1 shared Harsh AgrawaliD· 1 shared Humaira IlyasiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Alexandra SchurerORCID

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2 papers

Recent·Most cited

Cell BiologyLife Science AlliancePeer-reviewedJan 21, 2026

Proliferative events ameliorate DNA damage accumulation without affecting function in hematopoietic stem cells

Shubham Haribhau Mehatre, Harsh Agrawal, Irene Mariam Roy…·Satish Khurana

This study shows that increased HSC proliferation reduces age-related DNA damage without affecting function in mice.

DOI 10.26508/lsa.202503337

𝕏 PostBluesky

Cancer BiologybioRxivPreprintApr 7, 2025

TTLL4 glutamyltransferase is a therapeutic target for NPM1-mutated acute myeloid leukemia

Alexandra Schurer, Humaira Ilyas, Maxim I. Maron…·David Shechter

This study identifies TTLL4 as a therapeutic target in NPM1-mutated AML by showing its role in stabilizing NPM1c and promoting differentiation block, with a small molecule inhibitor demonstrating efficacy.

DOI 10.1101/2025.04.07.647605

𝕏 PostBluesky